By Susan L. McElroy, Paul E. Keck Jr., Robert M. Post
Several antiepileptic medications (AEDs) now have regulatory symptoms for treating bipolar affliction. there's starting to be proof that AEDs commonly have quite a few worthy psychotropic results. Antiepileptic medicinal drugs to regard Psychiatric issues is the 1st finished, clinically orientated reference at the use of AEDs to regard numerous psychiatric stipulations similar to temper, psychotic, anxiousness, substance use, consuming, and character problems. Written through the major medical specialists, the e-book is geared up via psychiatric illness for simpler info accumulating, allowing physicians to exploit the textual content as a standalone reference.
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Additional resources for Antiepileptic Drugs to Treat Psychiatric Disorders
To improve tolerability, AEDs generally need to be introduced with slow titration before reaching the first-target maintenance dosage. The necessary dosage titration time varies among AEDs from a few days for drugs such as gabapentin, levetiracetam, phenytoin, and valproate to several weeks for carbamazepine, lamotrigine, and topiramate (52). , seizure type, epilepsy severity, and patient preference) (52). If seizures continue, the dosage is gradually increased until seizures are controlled or until intolerable adverse effects occur.
38. Ben-Menachem E, Schmitz B, Tomson T, et al. Role of valproate across the ages. Treatment of epilepsy in adults. Acta Neurol Scand Suppl 2006; 184:14–27. 39. Mula M, Trimble MR, Yuen A, et al. Psychiatric adverse events during levetiracetam therapy. Neurology 2003; 61(5):704–706. 40. Perucca E, Beghi E, Dulac O, et al. Assessing risk to benefit ratio in antiepileptic drug therapy. Epilepsy Res 2000; 41(2):107–139. 41. Patsalos PN, Perucca E. Clinically important drug interactions in epilepsy: interactions between antiepileptic drugs and other drugs.
Acta Paediatr 2004; 93:174–176. 20. Artama M, Auvinen A, Raudaskoski T, et al. Antiepileptic drug use of women with epilepsy and congenital malformations in offspring. Neurology 2005; 64:1874–1878. 21. Wyszynski DF, Nambisan M, Surve T, et al. Increased rate of major malformations in offspring exposed to valproate during pregnancy. Neurology 2005; 64:961–965. 22. Morrow J, Russell A, Guthrie E, et al. Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register.