By Philip M. Parker
In March 2001, the nationwide Institutes of health and wellbeing issued the subsequent caution: "The variety of sites supplying health-related assets grows on a daily basis. Many websites offer precious info, whereas others can have info that's unreliable or misleading." additionally, a result of fast elevate in Internet-based details, many hours will be wasted looking out, deciding upon, and printing. seeing that purely the smallest fraction of knowledge facing Alstr?m syndrome is listed in se's, akin to www.google.com or others, a non-systematic method of net examine may be not just time eating, but in addition incomplete. This ebook used to be created for doctors, scholars, and individuals of most people who are looking to behavior scientific learn utilizing the main complicated instruments to be had and spending the smallest amount of time doing so.
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Extra info for Alstrom Syndrome - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers
Conditions caused by mutations in mitochondrial DNA often involve multiple organ systems. The effects of these conditions are most pronounced in organs and tissues that require a lot of energy (such as the heart, brain, and muscles). Although the health consequences of inherited mitochondrial DNA mutations vary widely, frequently observed features include muscle weakness and wasting, problems with movement, diabetes, kidney failure, heart disease, loss of intellectual functions (dementia), hearing loss, and abnormalities involving the eyes and vision.
The type of RNA that contains the information for making a protein is called messenger RNA (mRNA) because it carries the information, or message, from the DNA out of the nucleus into the cytoplasm. Translation, the second step in getting from a gene to a protein, takes place in the cytoplasm. The mRNA interacts with a specialized complex called a ribosome, which “reads” the sequence of mRNA bases. Each sequence of three bases, called a codon, usually codes for Help Me Understand Genetics 27 one particular amino acid.
In some cases, however, only one of the two copies is normally turned on. Which copy is active depends on the parent of origin: some genes are normally active only when they are inherited from a person’s father; others are active only when inherited from a person’s mother. This phenomenon is known as genomic imprinting. In genes that undergo genomic imprinting, the parent of origin is often marked, or “stamped,” on the gene during the formation of egg and sperm cells. This stamping process, called methylation, is a chemical reaction that attaches small molecules called methyl groups to certain segments of DNA.