By Philip M. Parker
In March 2001, the nationwide Institutes of well-being issued the next caution: "The variety of websites supplying health-related assets grows each day. Many websites supply worthy info, whereas others can have info that's unreliable or misleading." moreover, as a result of quick raise in Internet-based details, many hours could be wasted looking, settling on, and printing. given that purely the smallest fraction of knowledge facing Alexander ailment is listed in se's, corresponding to www.google.com or others, a non-systematic method of net study should be not just time eating, but additionally incomplete. This booklet used to be created for doctors, scholars, and contributors of most of the people who are looking to behavior scientific examine utilizing the main complex instruments on hand and spending the smallest amount of time doing so.
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Extra resources for Alexander Disease - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers
The signs and symptoms of some genetic conditions tend to become more severe and appear at an earlier age as the disorder is passed from one generation to the next. This phenomenon is called anticipation. Anticipation is most often seen with certain genetic disorders of the nervous system, such as Huntington disease, myotonic dystrophy, and fragile X syndrome. Anticipation typically occurs with disorders that are caused by an unusual type of mutation called a trinucleotide repeat expansion. A trinucleotide repeat is a sequence of three DNA building blocks (nucleotides) that is repeated a number of times in a row.
These changes most often occur in somatic cells (cells other than eggs and sperm) during a person’s lifetime. Can Changes in Mitochondrial DNA Affect Health and Development? Mitochondria are structures within cells that convert the energy from food into a form that cells can use. Although most DNA is packaged in chromosomes within the nucleus, mitochondria also have a small amount of their own DNA (known as mitochondrial DNA or mtDNA). In some cases, inherited changes in mitochondrial DNA can cause problems with growth, development, and function of the body’s systems.
Lifetime risk Lifetime risk is the average risk of developing a particular disorder at some point during a lifetime. ” It is important to remember that the risk per year or per decade is much lower than the lifetime risk. In addition, other factors may increase or decrease a person’s risk as compared with the average. Approximately 1 percent of people in the United States develop disorder D during their lifetimes. The lifetime risk of developing disorder D is 1 in 100. Naming Genetic Conditions Genetic conditions are not named in one standard way (unlike genes, which are given an official name and symbol by a formal committee).